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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Alcohol Clin Exp Res. 2013 Jun 13;37(10):1680–1687. doi: 10.1111/acer.12153

Figure 2. CRF potentiates NMDAR currents after binge ethanol drinking.

Figure 2

(A,B) (A) Example traces (inset) and data across time, and (B) averaged data showing enhancement of evoked NMDAR currents by 100 nM CRF in VTA neurons from binge-drinking mice but not from naïve mice. Scale bars in (A) represent 150 pA and 150 msec. “Baseline” and “CRF-wash” indicate that example traces were taken from the pre-CRF baseline and from 10 min after washout of CRF, a time point when the NMDAR currents were still enhanced. Numbers in each bar correspond to the n per group. * p < 0.05.