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a) Membrane currents in oocytes expressing mouse Panx1 induced by voltage pulses from -50 to + 50 mV. Glyburide (glibenclamide) attenuated the currents in a dose-dependent fashion. n=3-4. b) Connexin 46 currents in oocytes were not affected by glyburide. c) Dose-response relationship of Panx1 current inhibition by glyburide. d) ATP release by Panx1 expressing ooctes was stimulated by 150 mM potassium gluconate solution (KGlu) and inhibited by glyburide (100 μM).
