Extended Data Fig.6. VDJ sequences from all groups display different mutational patterns.
a, ggSeqLogos for light chain (top) and heavy chain (bottom) for all groups Fig. 5a. VDJ sequences were aligned, and germline residues are masked in white, all residue mutations are depicted as a single letter scaled to their frequency in that group's VDJs. Groups and sequences (n) are depicted in table to left.
b, Mutations from germline differing between groups where P value is Chi2 adjusted P value and positive or negative effect value for 1428 groups. Displayed top ~10% of total significant mutations found (P < 10–30).
c, Table of first LC codons occurrence in each group. Codons with a nucleotide substitution in positions 1 or 2 are translated as “X” deletions in alignments, but codon table shows their true residue translation (aa column).