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. Author manuscript; available in PMC: 2026 Sep 17.
Published in final edited form as: Nat Immunol. 2026 Jun 23;27(7):1476–1489. doi: 10.1038/s41590-026-02549-9

Extended Data Fig.5. VRC01gHL BGC cells from reimmunization comparisons and VDJ sequencing.

Extended Data Fig.5

a, Additional control groups for Fig.5a, providing 4 weeks maturation after final boost, giving 11 weeks total.

b, Left to right: Total BGC. Total BG505-WT binding VRC01gHL BGC cells. Total BG505-WT binding endogenous BGC cells.

a-b, Experiment was performed once. 8 week groups n=5; 11 week groups n = 4,3,3 respectively from left to right. Geometric means with SD plotted and Kruskal-Wallis uncorrected test; not significant (NS), P > 0.05; * P < 0.05; ** P< 0.01; *** P < 0.001; **** P < 0.0001.

c, BG505-WT probe staining and gates for all VRC01gHL BGC cells after 8 weeks, representing all animals sorted for VRC01gHL VDJ sequencing.