Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Transcriptionally impaired p53 does not downregulate CHK1. Exponentially growing H1299 cells expressing inducible wild-type p53 (WT) or the p53[22–23] mutant (22–23) were extensively washed to remove tetracycline. After the indicated hours, cells were harvested and subjected to Western blot analysis with antibodies specific for the indicated proteins. Actin was used as a normalizing control.
