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Antibody response patterns in cross-protection. The antibody responses to recombinant PspC and PspA in sera of mice immunized with PspC were measured by an ELISA, and log reciprocal titers were determined. Each bar on the graph represents the mean of the log reciprocal titer and the upper boundary of the standard error for sera from five mice. The limit of detection for the log reciprocal antibody titers in these assays was 1.8. CB, choline-binding region.
