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Estimates for required sample sizea
| Cytokine and stimulusb | Sample size for the following no. of determinations:
|
|
|---|---|---|
| 1 | 2 | |
| TNF-α | ||
| LPS | 14 | 8 |
| MAC | 12 | 8 |
| PPD | 49 | 26 |
| IFN-γ | ||
| PHA | 44 | 24 |
| MAC | 56 | 29 |
| PPD | 43 | 24 |
| Candida | 54 | 29 |
Size necessary to give 80% power to detect a twofold change, measured either once or twice at a 1-week interval, pre- and posttreatment, in blood diluted 10-fold.
MAC, M. avium complex.
