Table 1: Definitions of consensus symbols for Multiple Sequence Alignments generated by Clustal Omega.
The multiple species sequence alignment shown in Figure 2 was generated using Clustal Omega52. Abbreviations: serine (S), threonine (T), alanine (A), asparagine (N), glutamic acid (E), glutamine (Q), lysine (K), aspartic acid (D), arginine (R), methionine (M), isoleucine (I), leucine (L), phenylalanine (F), histidine (H), tyrosine (Y), tryptophan (W), cysteine (C), valine (V), glycine (G), proline (P).
| Symbol | Level of Amino Acid Conservation | Grouped Amino Acids |
|---|---|---|
| Asterisk (*) | Fully-conserved residue | Not applicable (single, fully-conserved residue) |
| Colon (:) | Groups with strongly similar properties | STA; NEQK; NHQK; NDEQ; QHRK; MILV; MILF; HY; FYW |
| Period (.) | Groups with weakly similar properties | CSA; ATV; SAG; STNK; STPA; SGND; SNDEQK; NDEQHK; NEQHRK; FVLIM; HFY |
| Space (no symbol) | No similarity | Not applicable (no similarity) |