FIG. 2.
(A) Schematic representation of EntD and VibD. The proposed phosphopantetheinyl transferase consensus regions are shown (15). The most highly conserved amino acid residues are shaded. (B) Domain structure of EntF and VibH. The EntF protein contains condensation (amino acids 1 to 475), adenylation (amino acids 476 to 960), peptide carrier (961 to 1049), and thioesterase (amino acids 1050 to 1293) domains (10, 22), while VibH contains only a condensation domain. The proposed catalytic region for the condensation domain is shown, and the most highly conserved amino acids are shaded. The approximate amino acid number at the junctions of the domains is indicated.