. Author manuscript; available in PMC: 2023 Oct 1.

Published in final edited form as: J Acquir Immune Defic Syndr. 2022 Oct 1;91(2):175–181. doi: 10.1097/QAI.0000000000003032

Table 3.

Sex-specific adjusted rate ratios of incident heart failure in people with HIV, by HIV severity, compared with people without HIV

HIV severity^a	Men N=373,244			Women N=52,193
HIV severity^a	Cases of HF	Adjusted^b RR (95% CI)	p	Cases of HF	Adjusted^b RR (95% CI)	p	P for interaction
Recent CD4 (cells/μl)
PWoH	3,002	Reference		296	Reference
PWH, ≥500	60	1.09 (0.84–1.40)	0.54	12	1.50 (0.84–2.68)	0.18
PWH, 200–499	90	1.71 (1.39–2.12)	<0.001	16	2.80 (1.68–4.66)	<0.001	0.05
PWH, <200	42	2.97 (2.19–4.04)	<0.001	10	5.30 (2.80–10.05)	<0.001
Nadir CD4 (cells/μl)
PWoH	3,002	Reference		296	Reference
PWH, ≥500	21	0.94 (0.61–1.44)	0.77	4	1.38 (0.51–3.70)	0.52
PWH, 200–499	100	0.93 (0.76–1.14)	0.50	16	1.39 (0.84–2.32)	0.20	0.08
PWH, <200	207	1.50 (1.30–1.73)	<0.001	31	2.17 (1.48–3.17)	<0.001
Recent HIV RNA (copies/ml)
PWoH	3,002	Reference		296	Reference
PWH, ≤200	115	1.41 (1.17–1.70)	<0.001	13	1.33 (0.76–2.34)	0.31
PWH, 201–9,999	40	1.70 (1.25–2.33)	<0.001	12	3.47 (1.93–6.25)	<0.001	0.01
PWH, ≥10,000	37	2.70 (1.59–3.05)	<0.001	13	5.54 (3.15–9.76)	<0.001

Abbreviations: HF=heart failure, RR=rate ratios, CI=confidence interval, PWH=people with HIV, PWoH=people without HIV

Reference: People without HIV (3,002 cases of HF among men without HIV; 296 cases of HF among women without HIV); Recent CD4 and recent HIV RNA measures were time-updated.

Poisson models were adjusted for sex, age, race/ethnicity, neighborhood-level income, obesity, cardiovascular disease, hypertension, diabetes mellitus, hyperlipidemia, ever smoking, ever alcohol use disorder, and ever drug use disorder.