FIGURE 4.
TRF decreased circulating pro-inflammatory cytokines in hypertensive mice. Serum levels of pro-inflammatory cytokines (a) IL-6 and (b) IL-1b in mice with LHTN and SSHTN. Results are expressed as dot plots with mean ± SEM. For IL-6 calculations, n = 4 for each group. For IL-1b calculations, n = 8 for each LHTN group and n = 6 for each SSHTN group. ∗P < 0.05 compared to the non-TRF group. LHTN, L-NAME-induced hypertension; SSHTN, salt-sensitive hypertension; TRF, time restricted feeding; SEM, standard error of mean.