Table 9.
Features of microvessel models fabricated by guided capillary angiogenesis
| Purpose | Measurement | Co–culture | Diameter | ECM | Ref. |
|---|---|---|---|---|---|
|
| |||||
| Design of a microfluidic platform to model angiogenesis | Interaction between hepatocytes and ECs | HUVEC, fibroblasts, hepatocytes | 10–100 μm | Collagen | 108 |
| Control over perfusable angiogenesis platform using varying co-culture and growth factors | Perfusable segments (fluorescent beads), area coverage, branch number, and diameter | Stromal cells, ECs | 10–100 μm | Fibrin | 109 |
| Cell migration into matrix as a function of different co-cultures | EC migration into matrix | HMVEC, MTLn2/U87MG, 10T1/2 | 10–100 μm | Collagen | 107 |