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. Author manuscript; available in PMC: 2022 Nov 22.
Published in final edited form as: Curr Biol. 2021 Sep 22;31(22):4898–4910.e4. doi: 10.1016/j.cub.2021.09.004

Figure 2: RNA-seq analysis of null mutations in 14 human spliceosomal protein orthologs.

Figure 2:

A. Schematic of the RNA-seq pipeline.

B. Definitions of splicing events quantified.

C. Definitions of changes to Percent Spliced In (delta PSI or Δψ) values for intron retention, alternative 3’ splice site, and alternative 5’ spice site events.

D. Changes in transcript levels in mutants. Plotted is the total number of splicing factors changed in the RNA-seq data as well as total transcriptome changes. See also Table S1.