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. 2022 Mar 14;14:858162. doi: 10.3389/fnagi.2022.858162

TABLE 1.

Demographic and clinical characteristics of the cohort.

CT AD patients MD patients MCI p-values
n. 250 177 132 115
Gender (M:F) 82:168 52:125 40:92 45:70 p = 0.33
Age, y 79.35 ± 5.931 77.54 ± 5.07 80.34 ± 4.862 77.94 ± 5.42 p < 0.001
MMSE 29.0; 27.0–30.0 21.0; 18.3–23.73 21.2; 18.0–24.03 27.0; 26.0–28.04 p < 0.001
ApoE ε4 carriers (%) 20.4 49.15 30.46 27.3 p < 0.001

CT, subject without cognitive decline; AD, subjects with Alzheimer’s disease; MD, subjects with mixed Dementia; MCI, subjects with Mild Cognitive Impairment; MMSE, Mini-Mental State Examination.

1p < 0.03 vs. MCI and vs. AD; 2p < 0.001 vs. MCI and vs. AD; 3p < 0.001 for AD vs. CT; AD vs. MCI; MD vs. CT; MD vs. MCI; 4p < 0.003 vs. CT; 5p < 0.001 vs. CT, vs. MCI and vs. MD; 6p = 0.043 vs. CT. Bold values are indicate a statistically significant p-value.