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. 2022 Mar 28;13:1644. doi: 10.1038/s41467-022-29143-5

Table 1.

Summary of the 2030 genetic association signals by metabolite biochemical class.

Biochemical class and abbreviation Total metabolites Significant metabolites Total signals Novel signals
Lipid (LI) 548 357 903 74
Amino acid (AA) 215 154 441 73
Xenobiotics (XE) 163 52 91 16
Nucleotide (NU) 42 26 65 29
Peptide (PE) 42 18 28 7
Cofactors and vitamins (CV) 38 25 69 27
Carbohydrate (CA) 25 20 38 7
Energy (EN) 10 4 11 3
Partially characterized (PC) 16 8 20 1
Unnamed (UN) 292 139 364 66
Total 1,391 803 2,030 303

Significant metabolites: number of metabolites with at least one association signal at P < 7.2 × 10−11.