Figure 7. The TCR repertoires for subjects in the ‘Asian’-associated PCA-cluster contain fewer N-insertions for productive TCRs when compared to the population mean computed across all 666 subjects (dashed, red horizontal line).
The p-values from a one-sample t-test (without Bonferroni multiple testing correction) for each PCA cluster compared to the population mean are reported at the top of the plot.
Figure 7—source data 1. PCA-cluster and average number of N-insertions by subject.
elife-73475-fig7-data1.txt (38.7KB, txt)
Figure 7—figure supplement 1. The population mean is dominated by subjects in the ‘Caucasian’-associated PCA-cluster.
Of the 398 subjects in the sample population, 81% are in the ‘Caucasian’-associated PCA-cluster.