Table 1.
Assessment of data reconstruction quality
| Publication | MS G1 | MS G2 | HR [CI] |
|---|---|---|---|
| Bang et al. (2020) [37] | 5.80 (5.88) | 4.30 (4.44) | 0.83 [0.53, 1.31] (0.82 [0.52, 1.29]) |
| Becker et al. (2020) [39] | not defined | 6.00 (6.21) | 5.50 (5.51) |
| Bellmunt et al. (2017) [45] | 3.30 (3.24) | 2.10 (2.08) | 0.98 [0.81, 1.19] (0.93 [0.77, 1.13]) |
| Cortes et al. (2019) [46] | 4.90 (4.94) | 4.70 (4.72) | 0.63 (0.62) |
| Ferris et al. (2016) [41] | 2.00 (2.02) | 2.30 (2.29) | 0.89 [0.70,1.13] (0.89 [0.70,1.14]) |
| Fradet et al. (2019) [47] | 3.30 (3.35) | 2.10 (2.16) | 0.96 [0.79, 1.16] (0.92 [0.77, 1.11]) |
| Godfrey et al. (2018) [36] | – | – | 1.40 [0.54, 3.61] (1.40 [0.53, 3.69]) |
| Golan et al. (2019) [38] | 18.90 (18.90) | 18.10 (18.10) | 0.91 [0.56, 1.46] (0.88 [0.55, 1.42]) |
| Hammel et al. (2019) [35] | 21.20 (21.36) | 6.00 (5.93) | 0.72 [0.41, 1.27] (0.72 [0.42, 1.24]) |
| Jones et al. (2020) [34] | 26.00 (26.00) | 20.0 (18.80) | 0.59 [0.34, 1.05] (0.58 [0.33, 1.02]) |
| Jones et al. (2018) [33] | 15.10 (15.08) | 8.10 (8.02) | 0.72 [0.45, 1.17] (0.71 [0.44, 1.15]) |
| Kotani et al. (2019) [48] | 8.60 (8.62) | 8.00 (8.02) | 0.74 [0.48, 1.14] (0.72 [0.47, 1.11]) |
| Kreuzer et al. (2020) [50] | 19.40 (19.40) | 20.90 (21.30) | 1.22 [0.60, 2.47] (1.26 [0.62, 2.56]) |
| Lu et al. (2018) [40] | 4.63 (4.68) | 4.23 (4.33) | 0.78 [0.60, 1.00] (0.74 [0.55, 1.01]) |
| Malone et al. (2020) [49] | – | – | 0.66 [0.41, 1.07] (0.68 [0.42, 1.10]) |
| Motzer et al. (2015) [42] | 4.60 (4.46) | 4.40 (4.07) | 0.88 [0.75, 1.03] (0.87 [0.98, 1.34]) |
| Mukai et al. (2019) [44] | 27.90 (27.90) | 16.60 (16.60) | 0.55 [0.23, 1.29] (0.55 [0.23, 1.29]) |
| Toxopeus et al. (2018) [43] | – | – | 1.02 [0.75, 1.39] (1.01 [0.75, 1.39]) |
Quality of data reconstruction regarding the published median survival (MS) in group 1 and 2 (G1 and G2), the hazard ratio (HR) with 95% confidence intervals (CI). For each study the published statistics are given with the corresponding statistics of the reconstructed data in parentheses. Three studies did not report MS (−) and two did not provide confidence intervals