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. Author manuscript; available in PMC: 2022 Jun 20.
Published in final edited form as: Nat Genet. 2021 Dec 20;54(1):30–39. doi: 10.1038/s41588-021-00961-5

Extended Data Fig. 3. Calibration of ρ-level genetic value credible interval with respect to proportion of causal effects and SNP-heritability in testing individuals.

Extended Data Fig. 3

Each row of panels corresponds to one heritability parameter hg2∈{0.05,0.1,0.25,0.5,0.8} and each column of panels corresponds to one polygenicity parameter pcausal ∈ {0.001, 0.01, 0.1 1}. The x-axis is the expected coverage of ρ-GV CI (ρ). The y-axis is the empirical coverage calculated as the proportion of ρ-GV CIs that contain the true genetic value for one simulation repeat. The dots and error bars are mean ± 1.96 s.e.m of the empirical coverage calculated from 10 simulation repeats.