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Sequence analysis of EID-1. (A) The predicted amino acid sequence for EID-1. The LXCXE motif (shaded) and acidic domains (underlined) are indicated. (B) Comparison of the aligned amino acid sequence of the putative Rb-binding domain of EID-1 with the known Rb-binding sites of BRG1, Elf-1, SV40 large T Ag, adenovirus E1A, and HPV-16 E7 protein is shown. The conserved sequences in the consensus EnLXCXE motif are shaded.
