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. 2021 Nov 9;28(4):611.e9–611.e16. doi: 10.1016/j.cmi.2021.11.002

Table 4.

Factors associated with long COVID syndrome by fitting univariable and multivariable logistic regression analyses

Parameters OR (95%CI) p AOR (95%CI) p
Gender:
 Male 1 1
 Female 2.78 (1.68–4.62) <0.0001 3.32 (1.78–6.17) <0.0001
Age, 10 years older 1.03 (1.01–1.04) 0.001 1.03 (1.01–1.05) 0.01
O2 therapy:
 No O2 1 1
 O2 therapy low–high flows 0.67 (0.38–1.19) 0.17 0.39 (0.19–0.82) 0.44
 CPAP/NIV/IOT 0.97 (0.55–1.71) 0.91 0.67 (0.29–1.55) 0.85
LOS, each day more 1.01 (0.99–1.03) 0.28 0.998 (0.97–1.03) 0.92
Comorbidities:
 No 1 1
 Yes 1.35 (0.86–2.11) 0.19 1.05 (0.597–1.84) 0.87
Smoking:
 Active 1 1
 Unknown 0.13 (0.03–0.52) 0.004 0.16 (0.04–0.75) 0.31
 Never 0.61 (0.37–0.997) 0.05 0.56 (0.31–1.01) 0.41
 Former 0.36 (0.14–0.96) 0.04 0.19 (0.06–0.62) 0.002
BMI:
 ≥30 1 1
 Unknown 0.29 (0.096–0.91) 0.03 0.13 (0.30–0.53) 0.03
 <30 0.55 (2.27–5.06) 0.02 0.55 (0.31–0.98) 0.28
Time from symptoms onset to virological clearance, each day more 1.01 (0.99–1.02) 0.64 0.99 (0.98–1.01) 0.47

Each variable is mutually adjusted.

Outcome, long COVID syndrome. AOR, adjusted odds ratio; CPAP, continuous positive airway pressure; OTI, orotracheal intubation; NIV, non-invasive ventilation; LOS, length of hospital stay; BMI, body mass index.