Table 3.
Transition of liver function between the start and end of lenvatinib according to Child-Pugh score
| Child-Pugh score | Migration to posttreatment after lenvatinib | ||||
|---|---|---|---|---|---|
| absent (%) | present (%) | p value | |||
| At the time of start of lenvatinib | |||||
| 5 | 35 (43.2) | 40 (58.8) | 0.155 | ||
| 6 | 31 (38.3) | 20 (29.4) | |||
| ≥7 | 15 (l8.5) | 8 (11.8) | |||
| At the time of end of lenvatinib | |||||
| 5 | 12 (14.8) | 24 (35.3) | <0.001 | ||
| 6 | 15 (18.5) | 20 (29.4) | |||
| ≥7 | 54 (66.7) | 24 (35.3) | |||
| Transition of liver function | |||||
| Improvement | 4 (4.9) | 5 (7.4) | 0.003 | ||
| Remaining | 20 (24.7) | 34 (50.0) | |||
| Worsening | 57 (70.4) | 29 (42.6) | |||