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Autoradiograph visualizing telomeric DNA. Halo preparations were digested with StyI and centrifuged to separate S and P telomeric sequences. Lanes show total (T; P plus S), S, and P telomeric DNA fractions in spermatogonia of Atm null (a) and control (b) mice. Lanes P and S for control mice and lanes P and S for Atm null mice represent telomeric DNA from similar numbers of halos. Note the difference in the P/S fraction ratio between Atm null and control mouse cells.
