TABLE 1.
Clinical signs and symptoms and laboratory findings of 16 patients who were positive for M. pneumoniae in any of the four diagnostic tests
| Patient | Period of disease at first sampling (days) | Age | ESRa | Leukocyte count (109/liter) | Chest radiograph abnormalities | CFT titerb in sample:
|
Result of:
|
Diagnosis of M. pneumoniae infectionc | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IgM IFA | PCR on throat specimens at:
|
Culture | ||||||||||
| 1 | 2 | AMC (n = 92) | SSI (n = 16) | |||||||||
| 1 | 11 | 14 | 110 | 11.5 | + | ≥128 | ≥128 | + | + | + | + | + |
| 2 | 7 | 9 | 76 | 7.0 | + | ≥128 | ≥128 | − | + | + | + | + |
| 3 | 5 | 3 | 25 | 11.7 | − | 32 | ≥128 | + | + | + | + | + |
| 4 | 28 | 5 | 15 | 12.3 | − | 32 | ≥128 | + | − | − | − | + |
| 5 | 14 | 1 | 61 | 12.3 | + | ≥128 | NAd | + | + | + | − | + |
| 6 | 7 | 13 | 16 | 14 | − | ≥128 | 64 | + | − | − | − | + |
| 7 | 6 | 9 | NT | 6.7 | + | 32 | 32 | + | + | + | + | + |
| 8 | 7 | 9 | 43 | 7.2 | + | ≥128 | ≥128 | + | + | + | + | + |
| 9 | 5 | 16 | 24 | 7.5 | − | 64 | 64 | − | + | + | + | + |
| 10 | 17 | 3 | 11 | 6.8 | − | 16 | 8 | + | − | − | − | − |
| 11 | 7 | 7 | 4 | 8.5 | − | 32 | 32 | + | − | − | − | − |
| 12 | 14 | 6 | 43 | 11.3 | + | 32 | 32 | + | − | − | − | − |
| 13 | 18 | 2 | 34 | 7.9 | + | 32 | 16 | + | − | − | − | − |
| 14 | 4 | 7 | 5 | 9.1 | NA | 8 | 8 | + | − | − | − | − |
| 15 | 3 | 2 | 5 | 12.5 | NA | 64 | 64 | + | − | − | − | − |
| 16 | 3 | 3 | 32 | 37.8 | NA | 32 | 32 | + | − | − | − | − |
a
ESR, erythrocyte sedimentation rate; NT, not tested.
b
From 65 of the 92 included patients a second serum sample was collected 2 to 3 weeks after the first sample. CFT positivity was defined as ≥128 or a fourfold titer rise.
c
Defined as positive culture and/or positive CFT.
d
NA, not available.