Skip to main content
. 2021 Jun 8;184(15):3936–3948.e10. doi: 10.1016/j.cell.2021.06.005

Figure 2.

Figure 2

Characterization of mAbs derived from vaccine plasmablasts

(A–D) Binding of plasmablasts derived from three vaccinees (V3, V5, and V6) against full-length spike (A), RBD (B), NTD (C), and S2 (D).

(E) The percentages of the respective antibodies per subject.

(F and G) Neutralizing activity of the mAbs against authentic SARS-CoV-2 (F) and the proportion of neutralizing antibodies per subject is shown in (G).

(H and I) Reactivity of mAbs to spike protein of human β-coronaviruses OC43 and HKU1.

MBC, minimal binding concentration. All experiments except data shown in (H) and (I) were performed in duplicates and the mean of the duplicates is shown with standard deviation. For (H) and (I), a representative dataset from a singlet ELISA run is shown.