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PalGly-induced calcium influx in a large subset of native adult DRG cells. A, a single cell trace of a primary adult DRG cell treated with PalGly (16 μM) after 60 s of baseline recording. B, average increase in calcium influx after PalGly application (for cells that responded with an average >50 nM calcium increase over baseline), was significantly different from the average increase after vehicle treatment [total cells; C; t(54) = 12.4; two-tailed; ***, p < 0.001].
