Table 1.
Effects of AlloP on the NFLT, NDS, and density of damaged cells in the GCL
| Condition | NFLT vs. RT (%) [p value vs. 75 mm Hg] | NDS [p] | Damaged cells in GCL [p] |
|---|---|---|---|
| 10 mm Hg [reference] |
1.5 ± 0.7 | 0.2 ± 0.4 | 1.9 ± 1.8 |
| 75 mm Hg [-] |
11.4 ± 1.9 [-] |
0.8 ± 0.4 [-] |
17.0 ± 5.0 [-] |
| 75 mm Hg + AlloP [vs. 75 mm Hg] |
1.5 ± 0.6 [*p < 0.05] |
0.2 ± 0.4 [p > 0.05] |
2.0 ± 1.7 [*p < 0.05] |
| 75 mm Hg + AlloP +Picro [vs. 75 mm Hg] |
4.0 ± 2.6 [*p < 0.05] |
3.1 ± 0.8 [*p < 0.05] |
23.9 ± 6.6 [p > 0.05] |
| 75 mm Hg + Rapa [vs. 75 mm Hg] |
1.7 ± 0.5 [*p < 0.05] |
0.3 ± 0.5 [p > 0.05] |
6.9 ± 2.1 [*p < 0.05] |
| 75 mm Hg + Torin 2 [vs. 75 mm Hg] |
1.8 ± 0.6 [*p < 0.05] |
0.2 ± 0.4 [p > 0.05] |
8.1 ± 1.9 [*p < 0.05] |
| 75 mm Hg + AlloP +Baf [vs. 75 mm Hg] |
5.3 ± 1.4 [*p < 0.05] |
3.2 ± 1.3 [*p < 0.05] |
30.4 ± 8.2 [*p < 0.05] |
| 75 mm Hg + AlloP + SAR405 [vs. 75 mm Hg] |
6.4 ± 2.0 [p > 0.05] |
3.4 ± 1.0 [*p < 0.05] |
36.9 ± 6.9 [*p < 0.05] |
Data are mean ± SD. NFLT vs. retinal thickness (RT) (%) refers to the NFLT percentage of total RT. The density of damaged cells in the GCL was counted per 250 μm of retina. P values in each parameter were calculated by Tukey’s test vs. 75 mm Hg (see Source data of Table 1).