Table 2.
Frequencies of immune cell subsets associated with OS at baseline and at 7 and 10 weeks after treatment determined by manual gating analysis of mass cytometry data.
| CD8+CD45RO−CCR7−CD57+ | ||||||
|---|---|---|---|---|---|---|
| Best |
Poor/Worst |
|||||
| Time point | Median (%) | Range (%) | Median (%) | Range (%) | P value | N |
| Baseline | 8.3 | 0.3–14.3 | 0.9 | 0.1–19.8 | 0.0100 | 38 |
| Week 7 | 5.0 | 0.2–8.3 | 0.0 | 0.2–7.6 | 0.0286 | 25 |
| Week 10 | 4.7 | 0.2–9.0 | 0.6 | 0.1–3.3 | 0.0707 | 15 |
| CD14+CD33+CD85j+ | ||||||
| Best |
Poor/Worst |
|||||
| Time point | Median (%) | Range (%) | Median (%) | Range (%) | P value | N |
| Baseline | 14.0 | 3.6–54.1 | 20.2 | 3.5–46.1 | 0.0785 | 38 |
| Week 7 | 8.1 | 2.9–25.3 | 12.5 | 5.5–40.5 | 0.0355 | 25 |
| Week 10 | 12.0 | 3.0–20.4 | 24.9 | 18.7–33.0 | 0.0023 | 15 |
Note: P values calculated using unpaired t test.