Skip to main content
. Author manuscript; available in PMC: 2021 Oct 28.
Published in final edited form as: J Am Chem Soc. 2020 Oct 16;142(43):18599–18618. doi: 10.1021/jacs.0c08231

Figure 1.

Figure 1.

a. Hyperexcitatory compounds that antagonize GABAA receptors; b. cryogenic electron microscopy structure of the human α1β3γ2L GABAA receptors; c. channel binding site of picrotoxinin, which exhibits allosteric coupling to the extracellular region (b/c, Ref. 10).