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Increased protein aggregation (Ubiquitin), autophagy (p62/SQSTM1, Beclin-1, LC3B) and oxidative stress (4-HNE) markers in the RPE cells of PGC-1α KO, NFE2L2 KO and NFE2L2/PGC-1α dKO mice. Data represent average intensities from three different animals per genotype and n = 30. *p < 0.001 one-way ANOVA followed by Games-Howell post hoc test. Results are expressed as means ± SD. Colums represent similar results shown in the Felszeghy et al. (2019) Redox Biology publication.
