Table 1.
Baseline demographic and clinical characteristics of the hospitalized Covid-19 patients stratified by age
| Characteristic | All Patients (n=362) (100%) | <6S y (n=258) (71.3%) | ≥65 y (n=104) (28.7%) | p | |
|---|---|---|---|---|---|
| Age | 56 (46–67) | 50 (42–57) | 73 (68–81) | <0.001* | |
| Sex | 0.74 | ||||
| Male | 224 (61.9%) | 161 (62.4%) | 63 (60.6%) | ||
| Female | 138 (38.1%) | 97 (37.6%) | 41 (39.4%) | ||
| International travel history | 6 (1.7%) | 5 (1.9%) | 1 (1%) | 0.67 | |
| Contact history | 134 (37%) | 104 (40.3%) | 30 (28.8%) | 0.04* | |
| Smoker | 36 (9.9%) | 34 (13.2%) | 2 (1.9%) | 0.001* | |
| Alcohol | 2 (0.6%) | none | 2 (1.9%) | 0.08 | |
| Co-morbidities | |||||
| Any | 210 (58%) | 126 (48.8%) | 84 (80.8%) | <0.001* | |
| Hypertension | 138 (38.1%) | 73 (28.3%) | 65 (62.5%) | <0.001* | |
| COPD/asthma | 41 (11.3%) | 25 (9.7%) | 16 (15.4%) | 0.12 | |
| Coronary heart disease | 37 (10.2%) | 11 (4.3%) | 26 (25%) | <0.001* | |
| Congestive heart failure | 19 (5.2%) | 3 (1.2%) | 16 (15.4%) | <0.001* | |
| Cerebrovascular disease | 7 (1.9%) | 3 (1.2%) | 4 (3.8%) | 0.10 | |
| Chronic renal failure | 8 (2.2%) | 5 (1.9%) | 3 (2.9%) | 0.69 | |
| Liver disease | 4 (1.1%) | 1 (0.4%) | 3 (2.9%) | 0.07 | |
| Malignancy | 27 (7.5%) | 12 (4.7%) | 15 (14.4%) | 0.001* | |
| Immunosupression | 18 (5%) | 13 (5%) | 5 (4.8%) | 0.92 | |
| Number of co-morbidities Symptoms | 1 (0–2) | 0 (0–1) | 2 (1–2.7) | <0.001* | |
| Fever | 265 (73.2%) | 199 (77.1%) | 66 (63.5%) | 0.008* | |
| Cough | 304 (84%) | 227 (88%) | 77 (74%) | 0.001* | |
| Dry cough | 294 (81.2%) | 219 (84.9%) | 75 (72.1%) | 0.005* | |
| Dyspnea | 158 (43.6%) | 106 (41.1%) | 52 (50%) | 0.12 | |
| Fatigue/myalgia | 328 (90.6%) | 235 (91.1%) | 93 (89.4%) | 0.62 | |
| Sputum production | 10 (2.8%) | 8 (3.1%) | 2 (1.9%) | 0.73 | |
| Nausea (n=340) | 59 (17.4%) | 47 (18.2%) | 12 (12.9%) | 0.18 | |
| Diarrhea (n=340) | 47 (13.8%) | 36 (14%) | 11 (11.8%) | 0.51 | |
| Loss of smell/taste (n=340) | 26 (7.6%) | 23 (9.3%) | 3 (3.2%) | 0.068 | |
| Signs | |||||
| Body temperature (°C) | 37.2 (36.5–38.2) | 37.2 (36.5–38.2) | 37.3 (36.5–38.2) | 0.80 | |
| Fever (>38.3°C) | 71 (19.6%) | 53 (20.5%) | 18 (17.3%) | 0.48 | |
| Subfebrile temperature (37.8–38.3°C) | 49 (13.5%) | 28 (10.9%) | 21 (20.2%) | 0.02* | |
| Dyspnea (use of accessory muscles) | 113 (31.2%) | 62 (24%) | 51 (49%) | <0.001* | |
| Respiration rate (/min) | 18 (16–23) | 18 (16–22) | 20 (18–26) | <0.001* | |
| Respiration rate | |||||
| ≥30/ min | 25 (6.9%) | 11 (4.3%) | 14 (13.5%) | 0.002* | |
| SaO2 (%) | 96 (93–97) | 96 (94–98) | 94 (89–96) | <0.001* | |
| SaO2<90% | 13 (13%) | 21 (8.1%) | 26 (25%) | <0.001* | |
| Pulse rate (/min) | 94 (86–105) | 94 (88–105) | 95 (84.2–102) | 0.30 | |
| Need for oxygen support (SaO2< 93%) | 74 (20.4%) | 38 (14.7%) | 36 (34.6%) | <0.001* | |
| Clinically severe pneumonia | 114 (31.5%) | 63 (24.4%) | 51 (49%) | <0.001* | |
| Time from first symptom to hospitalization (d) | 5 (3–7) | 5 (3–7) | 5 (3–7) | 0.42 | |
Data are given as median (interquartile range) for the continuous variables and as counts (%) for the categorical variables; COPD: chronic obstructive pulmonary disease, d: days, min: minute, SaO2: oxygen saturation; *statistically significant