Figure 1.
Surgical implantation of the thyroid window. A, the hair on the anterior neck of the mouse is removed and the skin is sterilized with chlorhexidine. B, tumor exposure: a small circular incision is made over the palpable tumor. C, the salivary glands are gently retracted, exposing the tumor. D, the obstructing salivary gland is pinned to the skin. E, a circumferential purse-string suture is made around the open area. F, the window frame is placed into the incision and the purse-string suture tightened and tied. G, the window frame is gently lifted, tacking adhesive is applied to its underside, and the frame is placed in contact with the tumor, holding firm pressure for ~30 seconds. H, a small amount of adhesive is applied on the lower lip of the window frame bore, and the coverslip is placed inside sealing the neck space.