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. 2020 Jul 29;8:890. doi: 10.3389/fbioe.2020.00890

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Copyright © 2020 Hao, Liu, Gao, He, He, Zhao, Sun, Farmer, Panitch, Lam and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ECFC spreading and spouting in LXW7-modified collagen hydrogel. (A) Images of ECFC morphology in untreated collagen hydrogel (a) and LXW7-modified collagen hydrogel (b) after 1 day culture and ECFC morphology in untreated collagen hydrogel (c) and LXW7-modified collagen hydrogel (d) after 3 day culture. Scale bar = 100 nm. (B) Quantification of the cell area of ECFCs cultured in collagen hydrogel with different modification. (C) Quantification of the number of sprouts of ECFCs cultured in collagen hydrogel with different modification. Data were expressed as mean ± standard deviation: ^∗p < 0.05 (n = 5).