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. Author manuscript; available in PMC: 2020 Jul 28.
Published in final edited form as: Brain Behav Immun. 2017 Aug 30;67:181–193. doi: 10.1016/j.bbi.2017.08.021

Figure 8. Circadian timing influences efficacy of (+)-Naltrexone on relative change in conditioned chamber time.

Figure 8

There was a significant effect of pretreatment on alcohol-induced conditioned place preference time with mice in the dark cycle exhibiting a significant reduction between saline and (+)-Naltrexone in conditioned place preference time. All data was analysed using a two-way ANOVA with Tukey post hoc. Summary values represented as mean±SEM; n=8, *p < 0.05. saline# = saline conditioned mice.