Skip to main content
. 2020 Aug 1;88(3):248–259. doi: 10.1016/j.biopsych.2019.12.005

Figure 1.

Figure 1

Schizotypy-related magnetization (SRM): association between intracortical magnetization transfer (MT) and Schizotypal Personality Questionnaire (SPQ) score. (A) Cortical surface maps highlighting areas where SPQ total score was significantly positively correlated with regional MT after controlling for age by regression: pink regions had nominally significant SRM (2-tailed p < .05); red regions had significant SRM controlled for multiple comparisons over 68 cortical regions tested (false discovery rate < .05). (B) Scatterplot of SPQ total score for each participant vs. mean MT in regions of significant SRM (R2246 = .04, p = .002); each dot represents 1 of 248 healthy people 14 to 25 years of age. (C) Scatterplots of SRM vs. MT at 14 years of age (MT14) (left) (R267 = .34, permutation testing based on spherical rotations: p = .002) and SRM vs. change in magnetization 14 to 25 years of age (ΔMT) (right) (R267 = .28, permutation testing based on spherical rotations: p = .006). Each point represents a cortical region and colored points represent regions with significant SRM (pink: p < .05; red: false discovery rate < .05). (D) Word cloud representing ontological terms most frequently associated with functional activation of the medial posterior cortical areas of significant SRM. (E) Cortical surface maps highlighting areas where scores on the disorganized factor of schizotypy was significantly positively correlated with regional MT after controlling for age by regression (pink, 2-tailed p < .05; red, false discovery rate < .05).