Figure 1.
The phylogeny and sequence conservation of coronavirus nsp3. (A) Phylogeny of 15 strains based on the nsp3 protein sequence alignment and phylogeny analysis. (B) The conservation of nsp3 among different coronavirus strains. The red line represents the conservation among the four strains (SARS-CoV, SARS-CoV-2, MERS, and BtCoV-HKU3). The blue line was generated using all the 15 strains. The bottom part represents the nsp3 peptides and their sizes. The phylogenetically close four strains have more conserved nsp3 sequences than all the strains being considered.