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. 2020 May 20;12(5):e8206. doi: 10.7759/cureus.8206

Table 1. Summary of different types of mRNA-based vaccines [10].

Type of mRNA vaccine Mechanism of action  Comments
Conventional Genes encode only for the target antigen The antigen expression is only transient, so the immune response generated is weaker
Amplifying Genes encoding the RNA are intact but instead if structural proteins, the genes encode for the target antigen Higher antigen expression, although delayed effect. The immune response elicited lasts longer