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Selective cytotoxicity of molecular drugs (Dox) transported by aptNTrs. (A and B) MTS assay results showing that Dox transported by LZH5B-NTrs (LZH5B-NTr-Dox) selectively induced potent cytotoxicity and inhibited cell proliferation in target HepG2 cells (A), but not in non-target Hu1545 cells (B), in contrast to nonselective cytotoxicity induced by free Dox in both target and non-target cells.
