Table 2.
Laboratory Features of 22 Influenza A(H5N1) Infected Patients Who Survived or Died
| Measures | Survivors (n = 4) | Nonsurvivors (n = 18) | P Value |
|---|---|---|---|
| Hematology | |||
| Hemoglobin, g/dL | 13.25 (8.7–14.3) | 13.1 (11–16.2) | .76 |
| Total WBC count,/μL | 3,250 (2,330–4,700) | 2,740 (1,470–8,090) | .55 |
| Neutrophil count,/μL | 1,900 (970–2,960) | 2,400 (540–6,900) | .61 |
| Lymphocyte count,/μL | 860 (600–2,100) | 640 (280–1,750) | .12 |
| Platelet count,/μL | 133,000 (92,000–250,000) | 128,500 (40,000–260,000) | .86 |
| D-dimer, mg/L | 1.35 (0–2.3) | 2.6 (1.2–5.2) | .015 |
| DIC score | 2 | 2 | .21 |
| Biochemistry | |||
| Urea, mg/dL | 18 (15–27) | 47 (10–158) | .017 |
| Creatinine, mg/dL | 0.65 (0.4–1) | 1.2 (0.6–6.7) | .011 |
| Glucose, mg/dL | 84.5 (70–89) | 202 (115–468) | .0023 |
| Blood gases, preventilation | |||
| pH | 7.44 (7.4–7.49) | 7.41 (7.1–7.59) | .49 |
| Pco2, mm Hg | 29.3 (26.4–38.6) | 40.9 (23.5–90.3) | .17 |
| Po2, mm Hg | 98.6 (78–204) | 43.5 (20.9–91.8) | .005 |
| Po2:Fio2 ratio | 239 | 44 | .017 |
| HCO3−, mmol/L | 21.3 (18.5–23.3) | 22.6 (12.2–62.9) | .55 |
| Sao2, % | 98.1 (96.8–99.9) | 79.8 (19.5–98) | .0033 |
| Median SOFA score | 2.5 | 5.5 | .0058 |
Data are median, median (range) or No. DIC = disseminated intravascular coagulation; HCO3– = bicarbonate; Sao2 = arterial oxygen saturation; SOFA = Sepsis Organ-related Failure Assessment.