Skip to main content
. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: J Am Chem Soc. 2020 Jan 17;142(5):2087–2092. doi: 10.1021/jacs.9b10678

Table 1.

Reaction Optimizationa

graphic file with name nihms-1555525-t0004.jpg
entry variation from “standard conditions” yield (%)
1 none 90 (88)
2 no applied voltage <5
3 no light irradiation <5
4 no DCA <5
5 no pyridine 58
6 CFL (23 W) instead of blue LED 70
7 Al(+)/C(−) instead of Zn(+)/C(−) 65
8 undivided cell 37
9 AO as a catalyst instead of DCA 66
10 3 as substrate 57 (53)
a

Cathodic chamber: 1 (0.4 mmol, 1.0 equiv), DCA (5 mol%), B2pin2 (2.0 equiv), pyridine (20 mol%), TBAPF6 (0.15 M), CH3CN (0.1 M); anodic chamber: TBAPF6 (0.15 M), CH3CN (0.1 M); cell voltage (Ucell) = 3.2 V; yields determined by 1H NMR (isolated yield in parentheses).

graphic file with name nihms-1555525-t0005.jpg