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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Trends Cell Biol. 2019 Oct 14;29(11):854–861. doi: 10.1016/j.tcb.2019.08.009

Figure 2. Overview of Relative Basal Media Compositions.

Figure 2.

(A) Heatmap depicting relative concentrations of defined basal media components compared to those in adult human plasma (log2-transformed fold changes). Components not present in a medium are marked as absent. Values used to generate the heatmap are defined elsewhere [42]. *RPMI further contains vitamin B12 (3.69 nM). (B) Additional HPLM components that are absent from the defined formulations of basal media described in panel (A). Designations used to group metabolites are not intended to be exclusive. *RPMI contains 4-Hydroxyproline at a concentration (153 μM) nearly eightfold that defined in HPLM. Abbreviations: BME, Basal Medium Eagle; DMEM, Dulbecco’s Modified Eagle Medium; HPLM, human plasma-like medium; MEM, Minimal Essential Medium; RPMI, Roswell Park Memorial Institute; denotes RPMI 1640.