Table 3.
Multivariable Analysis of Moderate-to-Severe Sleep Disordered Breathing (AHI3 ≥ 15 Events per Hour) Across Smoking Categories Among US Hispanics/Latino Subjects According to Age and Sex
| Variable | Female Subjects Aged 18-34 Years |
Female Subjects Aged 35-54 Years |
Female Subjects Aged 55-76 Years |
Male Subjects Aged 18-34 Years |
Male Subjects Aged 35-54 Years |
Male Subjects Aged 55-76 Years |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (n = 1,683) |
(n = 4,173) |
(n = 2,531) |
(n = 1,423) |
(n = 2,548) |
(n = 1,505) |
|||||||
| OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | |
| Smoking status | ||||||||||||
| Never smoked | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) | ||||||
| Former smoker | < 5 cases | NA | 2.11 (1.22-3.66) | .008 | 1.10 (0.77-1.59) | .595 | 1.55 (0.59-4.03) | .370 | 1.18 (0.82-1.70) | .375 | 0.54 (0.36-0.79) | .002 |
| Current smoker | < 5 cases | NA | 1.53 (0.94-2.51) | .088 | 1.42 (0.84-2.39) | .194 | 1.26 (0.52-3.02) | .610 | 1.28 (0.88-1.86) | .204 | 0.50 (0.30-0.82) | .006 |
| Former/current combined (Ref = never smoked) | < 5 cases | NA | 1.83 (1.19-2.81) | .006 | 1.20 (0.85-1.69) | .292 | 1.37 (0.64-2.92) | .414 | 1.23 (0.92-1.64) | .170 | 0.52 (0.37-0.74) | < .001 |
| Pack-years (Ref = never smoked) | ||||||||||||
| < 20 pack-years | < 5 cases | NA | 1.84 (1.15-2.95) | .011 | 1.41 (0.94-2.11) | .093 | 1.39 (0.64-3.01) | .399 | 1.22 (0.88-1.70) | .228 | 0.64 (0.44-0.95) | .027 |
| ≥ 20 pack-years | < 5 cases | NA | 1.80 (1.00-3.24) | .052 | 0.90 (0.53-1.53) | .689 | < 5 cases | NA | 1.23 (0.80-1.88) | .347 | 0.42 (0.27-0.64) | < .001 |
| P-for-trend | NA | .0053 | .739 | .3992 | .1994 | .0001 | ||||||
| Smoking intensity (among current smokers; Ref = never smoked) | ||||||||||||
| Nondaily smoker | < 5 cases | NA | 0.62 (0.26-1.46) | .271 | 2.40 (0.96-6.01) | .062 | 1.38 (0.49-3.84) | .540 | 1.45 (0.84-2.50) | .183 | 0.91 (0.41-2.06) | .828 |
| 0-9 cigarettes/d | < 5 cases | NA | 1.45 (0.61-3.45) | .401 | 1.08 (0.56-2.10) | .814 | 0.92 (0.21-4.06) | .913 | 1.19 (0.63-2.28) | .591 | 0.44 (0.20-0.97) | .043 |
| ≥ 10 cigarettes/d | < 5 cases | NA | 2.72 (1.45-5.12) | .002 | 1.47 (0.64-3.36) | .366 | 1.44 (0.39-5.30) | 0.584 | 1.16 (0.65-2.06) | .617 | 0.43 (0.21-0.88) | .021 |
| P-for-trenda | NA | .004 | .3136 | .9684 | .5454 | .1349 | ||||||
Models adjusted for age within subgroups, as well as BMI, waist-to-hip ratio, field center, Hispanic/Latino national background, place of birth (within vs outside US mainland), health insurance status, educational attainment, annual household income, alcohol use level, hay fever, and menopausal status. See Table 1 legend for expansion of abbreviation.
a
P-for-trend calculation for smoking intensity performed while restricting the analysis to current smokers.