Figure 3. Major brain targets of mouse ipRGCs.
A sample of ipRGC brain targets is depicted in a quasi-sagittal schematic of the mouse brain. Below is a plot of innervation densities across ipRGC types, drawn after Berson and colleagues (Quattrochi et al., 2018) and incorporating additional information (Ecker et al., 2010; Hattar et al., 2006; Huang et al., 2019; Morin and Studholme, 2014; Zhao et al., 2014). Each blue dot indicates the approximate density of innervation by its size, a white dot indicates undetectable innervation, and lack of a dot indicates an absence of information. M5s and M6s are pooled because their projections were examined together for technical reasons. Abbreviations: AH, anterior hypothalamus; BST, bed nucleus of the stria terminalis; dLGN, dorsal lateral geniculate nucleus; IGL, intergeniculate leaflet; LH, lateral hypothalamus; MA, medial amygdala; OPN, olivary pretectal nucleus (with shell, s, and core, c, regions); PA, preoptic area, which includes the VLPO (ventrolateral preoptic area); PAG, periaqueductal gray; PHb, perihabenular zone; pSON, peri-supraoptic nucleus; SC, superior colliculus; SCN, suprachiasmatic nucleus; sPa, subparaventricular zone; and vLGN, ventral lateral geniculate nucleus.