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. Author manuscript; available in PMC: 2021 Mar 1.

Published in final edited form as: Addict Biol. 2019 Jul 3;25(2):e12800. doi: 10.1111/adb.12800

Table 4:

Results of PRS derived using COGA SRE GWAS summary statistics. P<0.0125 are in bold.

		AD		DSM-IV AD criterion count
Discovery dataset	Test dataset	R²	p value	R²	p value
SRE-T COGA-EA	SAGE-EA	2.48%	4.13E-07	1.37%	8.55E-07
SRE-T COGA-EA	OZALC-EA	0.34%	0.05	0.60%	1.14E-03
SRE-T COGA-AA	SAGE-AA	1.49%	6.10E-03	1.04%	1.72E-03
SRE-T COGA-AA	Yale-Penn-AA	0.36%	0.03	0.05%	0.33
SRE-5 COGA-EA	SAGE-EA	0.88%	2.37E-03	0.61%	1.08E-03
SRE-5 COGA-EA	OZALC-EA	0.14%	0.21	0.47%	3.85E-03
SRE-5 COGA-AA	SAGE-AA	0.53%	0.10	0.34%	0.07
SRE-5 COGA-AA	Yale-Penn-AA	0.0007%	0.92	0.03%	0.43