Table 5.
Regression Analysis of Secondary Outcomes—Linear Contrast With Higher Arm Less Nicotine
| Difference Between Arms in Change | p Value | |
|---|---|---|
| Carotid femoral pulse wave velocity | −0.167 (−0.402 to 0.069) | 0.164 |
| ≤20 pack-years, n = 27 | −0.471 (−0.834 to −0.107) | 0.014 |
| >20 pack-years, n = 70 | 0.031 (−0.271 to 0.332) | 0.839 |
| Heart rate | −1.190 (−3.050 to 0.670) | 0.207 |
| ≤20 pack-years, n = 31 | 2.647 (0.278 to 5.016) | 0.030 |
| >20 pack-years, n = 82 | −2.825 (−5.223 to −0.426) | 0.022 |
| Augmentation index,75 beats/min | 0.112 (−1.833 to 2.058) | 0.909 |
| Oxidized LDL | −1.113 (−5.458 to 3.232) | 0.612 |
| High-sensitivity CRP∗ | 0.039 (−0.221 to 0.299) | 0.769 |
| Tissue plasminogen activator∗ | −0.036 (−0.123 to 0.052) | 0.425 |
| Platelet activation inhibitor-1∗ | −0.007 (−0.131 to 0.116) | 0.906 |
| Systolic blood pressure | −2.158 (−4.789 to 0.472) | 0.107 |
| Diastolic blood pressure | −1.126 (−2.624 to 0.372) | 0.139 |
Values are regression coefficient (95% CI). Change in parameters adjusted for baseline of the outcome, baseline age (≤40 years, >40 years), sex (male, female), and smoking pack-years (≤20 pack-years, >20 pack-years).
CI = confidence interval; CRP = C-reactive protein; LDL = low-density lipoprotein.
∗
Log-transformed.