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. Author manuscript; available in PMC: 2019 Dec 10.
Published in final edited form as: Circulation. 2018 May 17;138(1):e35–e47. doi: 10.1161/CIR.0000000000000574

Table 1.

Summary of 5 Trials That Tested the Effects of Fish Consumption on BP

Authors, Year Country Intervention Regimen Control n Duration, d Net Mean Difference
(95% CI), mm Hg
Intervention Type DHA+EPA,
g/d
Systolic BP Diastolic BP
Von Houwelingen,39 1987 Netherlands Mackerel paste (100 g/d) 4.7 Meat paste 82 42 −0.30 (−3.07 to 2.47) −1.60 (−3.84 to 0.64)
Cobiac,40 1991 Australia Salmon and sardines (142 g/d) 4.5 Mixed vegetable oil 18 35 −1.4 (−9.44 to 6.64) −0.30 (−6.77 to 6.17)
Lindqvist,41 2009 Sweden Baked herring (150 g/d, 3 d/wk) 1.2 Baked lean pork and chicken 35 42 2.10 (−3.21 to 7.41) 0.80 (−2.87 to 4.47)
Hallund,42 2010 Denmark Marine trout (150 g/d) 3.2 Chicken 68 56 −2.00 (−7.55 to 3.55) −3.00 (−7.33 to 1.33)
Ramel,43 2010 Iceland, Spain, Ireland Cod (150 g/d, 3 d/wk) 0.3 Sunflower oil 139 56 2.0 (−0.7 to 4.7) −0.50 (−3.02 to 2.02)
Salmon (150 g/d, 3 d/wk) 2.1 Sunflower oil 139 56 −0.2 (−3.13 to 2.73) −0.5 (−3.02 to 2.02)

BP indicates blood pressure; CI, confidence interval; DHA, docosahexaenoic acid; and EPA, eicosapentaenoic acid.