Table III.
Regions showing ALFF differences between the AD patients and healthy controls (without and with GM correction)
| Brain regions | BA | Vol (mm3) | MNI coordinates (mm) | Maximum Z | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Without GM correction | ||||||
| PCC/PCu | 23/7/29 | 6,939 | −3 | −36 | 30 | −4.24 |
| Left LN | N/A | 1,593 | −21 | 6 | −6 | −3.65 |
| Right ALC | N/A | 459 | 15 | −48 | −21 | −3.52 |
| Left OFG | 11 | 351 | −6 | 33 | −21 | −2.77 |
| Left PHG/Hip | 35/36/28 | 3,078 | −30 | −18 | −24 | 4.34 |
| Right SFG/SMA | 6 | 2,079 | 3 | 3 | 69 | 4.01 |
| Left FG | 37 | 3,321 | −27 | −57 | 0 | 3.95 |
| Left SFG/SMA | 6 | 1,053 | −6 | −9 | 66 | 3.81 |
| Right PHG/Hip | 35/28 | 1,728 | 30 | −18 | −27 | 3.79 |
| Left PoCG | 40 | 1,107 | −30 | −33 | 48 | 3.55 |
| Left ITG/STG | 20/22 | 2,835 | −39 | −3 | −42 | 3.40 |
| With GM correction | ||||||
| PCC/PCu | 23/7/29 | 1,161 | −3 | −51 | 30 | −3.54 |
| Left LN | N/A | 1,161 | −18 | 3 | 6 | −3.43 |
| Right ALC | N/A | 1,296 | 15 | −48 | −18 | −3.60 |
| Left PHG/Hip | 35/36/28 | 1,134 | −30 | −18 | −24 | 4.20 |
| Left FG | 37 | 3,240 | −33 | −57 | −15 | 4.09 |
| Left PoCG | 40 | 621 | −30 | −33 | 48 | 3.82 |
| SFG/SMA | 6 | 1,053 | 3 | 3 | 69 | 3.51 |
| Left ITG/STG | 20/22 | 1,350 | −39 | −3 | −39 | 3.48 |
| Right PHG/Hip | 35/28 | 783 | 33 | −3 | −27 | 3.15 |
x, y, z, coordinates of primary peak locations in the MNI space; Z statistical value of peak voxel showing ALFF differences between the AD subjects and healthy elders (negative values: AD < NC; positive values: AD > NC). ALC, anterior lobe of cerebellum; BA, Brodmann's area; FG, fusiform gyrus; Hip, hippocampus; ITG, inferior temporal gyrus; LN, lentiform nucleus; N/A, not applicable; OFG, orbitofrontal gryus; PCC/PCu, posterior cingulate cortex/precuneus; PHG, parahippocampal gyrus; PoCG, postcentral gyrus; SFG, superior frontal gyrus; SMA, supplementary motor area; STG, superior temporal gyrus. P < 0.05, corrected for multiple comparisons.