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. 2010 Nov 12;32(10):1720–1740. doi: 10.1002/hbm.21140

Table III.

Regions showing ALFF differences between the AD patients and healthy controls (without and with GM correction)

Brain regions BA Vol (mm3) MNI coordinates (mm) Maximum Z
x y z
Without GM correction
PCC/PCu 23/7/29 6,939 −3 −36 30 −4.24
Left LN N/A 1,593 −21 6 −6 −3.65
Right ALC N/A 459 15 −48 −21 −3.52
Left OFG 11 351 −6 33 −21 −2.77
Left PHG/Hip 35/36/28 3,078 −30 −18 −24 4.34
Right SFG/SMA 6 2,079 3 3 69 4.01
Left FG 37 3,321 −27 −57 0 3.95
Left SFG/SMA 6 1,053 −6 −9 66 3.81
Right PHG/Hip 35/28 1,728 30 −18 −27 3.79
Left PoCG 40 1,107 −30 −33 48 3.55
Left ITG/STG 20/22 2,835 −39 −3 −42 3.40
With GM correction
PCC/PCu 23/7/29 1,161 −3 −51 30 −3.54
Left LN N/A 1,161 −18 3 6 −3.43
Right ALC N/A 1,296 15 −48 −18 −3.60
Left PHG/Hip 35/36/28 1,134 −30 −18 −24 4.20
Left FG 37 3,240 −33 −57 −15 4.09
Left PoCG 40 621 −30 −33 48 3.82
SFG/SMA 6 1,053 3 3 69 3.51
Left ITG/STG 20/22 1,350 −39 −3 −39 3.48
Right PHG/Hip 35/28 783 33 −3 −27 3.15

x, y, z, coordinates of primary peak locations in the MNI space; Z statistical value of peak voxel showing ALFF differences between the AD subjects and healthy elders (negative values: AD < NC; positive values: AD > NC). ALC, anterior lobe of cerebellum; BA, Brodmann's area; FG, fusiform gyrus; Hip, hippocampus; ITG, inferior temporal gyrus; LN, lentiform nucleus; N/A, not applicable; OFG, orbitofrontal gryus; PCC/PCu, posterior cingulate cortex/precuneus; PHG, parahippocampal gyrus; PoCG, postcentral gyrus; SFG, superior frontal gyrus; SMA, supplementary motor area; STG, superior temporal gyrus. P < 0.05, corrected for multiple comparisons.