Fig. 2. Change analysis of metabolic variables during the randomization.
Effects on aging/disease markers and risk factors in all subjects who completed the randomized analysis in either the control arm or the FMD arm (5 to 7 days after the third cycle of FMD). (A) Body weight, (B) BMI, (C) total body fat, (D) trunk fat, (E) lean body mass, (F) waist circumference, (G) serum glucose level, (H) insulin-like growth factor 1, (I) systolic blood pressure, (J) diastolic blood pressure, (K) triglycerides, (L) total cholesterol, (M) LDL, (N) HDL, and (O) CRP were measured in both cohorts as described. The Δ change represents a comparison to baseline. All data are means ± SD. Between-arm comparisons were calculated using two-tailed two-sample equal variance t tests. For some of the 100 enrolled participants, the nurses were unable to collect all the samples/measurements from all subjects. We therefore excluded subjects with incomplete measurements from a particular marker group (see Table 2 for details). Abs, absolute; Rel, relative; BP, blood pressure.