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. Author manuscript; available in PMC: 2019 Oct 23.
Published in final edited form as: Brain Behav Immun. 2010 Nov 24;25(3):483–493. doi: 10.1016/j.bbi.2010.11.011

Figure 4: LPS (100 μg/mouse i.p.) strongly induces the expression of the full-length (A) and short (B) IL-18Rβ in the C57BL6/J mouse brain.

Figure 4:

Adult mice were injected i.p. with LPS (100 μg/mouse, n=3) (white bars) or saline (100 μl/mice n=3) (black bars) and then sacrificed 3 hrs after injection. The relative expression levels of IL-18Rβ mRNA variants in brain areas: frontal cortex, olfactory bulb, striatum, hypothalamus, thalamus, hippocampus, cerebral cortex and cerebellum, were evaluated by real time PCR using specific primers. Data were expressed as fold-change above the expression of the respective cerebral cortex of control (saline injected) animals (see Methods for equation used). Bars indicate the mean ± S.E.M. * Statistical significant difference between LPS injected and control (saline injected) animals. *p < .05.