Fig. 7.
The golli proximal promoter is active in CNS neurons that normally express the gene during embryogenesis.A, Whole-mount E11.5 embryo from transgenic mouse line 1.3D stained with X-gal. Expression of the lac Ztransgene was present in the olfactory placode (OP) and olfactory epithelium (OE). B, Whole-mount E13.5 embryo from transgenic mouse line 1.3D stained with X-gal. Expression of the lac Z transgene was evident within the forebrain (F), olfactory bulb (OB), and olfactory epithelium (OE). We also detected variable and inconsistent X-gal staining in the kidney (K), which was not investigated further.C, Dorsal view of an E13.5 embryo revealing expression of the lac Z transgene in dorsal root ganglia (D) and ventral root fibers (V). Scale bar: in A, 1.1 mm; in B, 1.9 mm; in C, 1 mm.