Fig. 4.
Augmenting responses in the minimal model of RE-TC-CX-IN cells during repetitive 10 Hz stimulation. Both the RE and TC cells were stimulated with 100% of maximal intensity, and the CX and IN cells were stimulated with 10% of maximal intensity. A, Monosynaptic stimulation of the CX cell elicited a nonaugmenting component in the cortical EPSPs that occurred simultaneously with EPSPs in the RE and TC cells. Augmenting spike bursts in TC cells lead to a growing secondary EPSPs in the CX cell. B, Same response shown on a shorter time scale. C, Superimposed traces of the first four EPSPs in a CX cell.Open circles indicate the time of thalamic stimulation (gAMPA = 0.1 μS from CX to IN, gAMPA = 0.1 μS from CX to TC, gAMPA = 0.2 μS from CX to RE, gGABAA = 0.03 μS from IN to CX, gAMPA = 0.035 μS from TC to CX, and gAMPA = 0.02 μS from TC to IN).